St. Luke Catholic Hospital and College of Nursing and Midwifery is situated in Wolisso Town, the capital of the South west Shoa Zone, Oromia Regional State. The hospital and college are owned by the Ethiopian Catholic Church.

The hospital began services on January 1st, 2001. There are now 200 beds in use for medical (35), surgical (24), pediatric (65), neonatal unit (6), ophthalmology, orthopedics (32), maternity (24) and gynecology (14). The hospital provides an outpatient department, antenatal and under five clinics, public health department with outreach services.

The Dining Room donates five percent of its profits to the hospital.